30 californian cabin subfloor

[ALASKAN]

I recently purchased a Californian 30 LRC. So far I have gotten the engine up and running well, and gone through the plumbing and electrical. It all looks and functions pretty well but the previous owner hadn't finished connecting the windlass. Its a lofran condor and I'm having trouble finding info. Other than that the engine is very hard to get to, and when I noticed the stuffing box leaking rather quickly, I decided to take the plunge and cut out a panel of the plywood subfloor in front of the door to the cabin. Big surprise, the whole frame for the wheelhouse floor was supported by two vertical 2x4's and the rear end of the floor dropped an inch and a half when I took that piece of plywood out. The plywood subfloor on the port side is pretty rotten so I'm going to replace that as well. Most likely, I will make the whole floor into a system of access hatches so I never have any trouble working in any part of the engine room.
My question is this: how much impact does the configuration of 2x4 framing for the subfloor affect the stability of the hull? Can I change the spacing for the 2x4's when I make the access hatches? Any suggestions would be greatly appreciated, I would like to get this floor buttoned up again asap. There were a ton of videos on YouTube about replacing boat floors but they were mostly bass fishing boats or other boats without a wheelhouse/cabin. Also sorry in advance is this is the wrong part of the site to post this on. Thanks team,
Respectfully,
JB