I replaced the curved windows in the corners of my Willard wheelhouse just that way. I did use machine screws all the way around. I kind of like the look if done neatly.
However I used MarGard Lexan not glass. Lexan can be cut, drilled, and rounded over with woodworking tools, it is 10x stronger than even tempered glass & does not sweat. Important I would think in your case, it will move as your structure works.
I don't think it would cost any more than having glass cut and edged. I used Lexan sealant and placed stick on silicone dots (1/8") around the edges to prevent squeezing out all the sealant while bending the Lexan & tightening the machine screws. Unless you are going to run a wiper on it, you don't even need MarGard, just plain Lexan will do.