If single v twins is your only issue, you need to go aboard both kinds. Get down and dirty in the ER of both. Drive both. Dock both. Dock both in a cross wind and in a cross current.
I once helped a friend learn the ins and outs of his ER in a 36 GB with twins. There was lots of room for both of us in the ER at once. Lots of access to everything that was to eventually be serviced. Mind you, neither of us needed to go to weight watchers, but had that been the case, he wouldn't have been able to service a single in the same ER.
The added maneuverability of twins would be enough to convince me, but I recently had a full summer while my mechanic waited for me to return from my boating vacation, in order to repair one of my engines. I lost no time from doing what I love to do, cruising on my boat. If I only had the one, I would have lost a summer. That alone would also be enough to convince me to go with twins.
You will burn more fuel with twins. That is not due to any extra cost of spinning the extra iron, but will be due to your enjoyment of 8 to 8.5 knot cruising instead of 6 to 7 knot cruising. If you still want to go that slow, your fuel consumption will drop to that of the guys with singles. Try both speeds. See which one you like. 8 to 8.5 knots would again be enough to convince me to go with twins.
You mentioned "the advantages of a single over twins". I don't think you have considered the opposite. You owe it to yourself to consider twins. Then you can make your choice and join the camp that you will then be able to properly defend, from true knowledge, not just from religion.