Depoe Bay has a well deserved reputation for being a difficult entrance. And once in you won't find a lot of dock space available.
Charlie's Charts US Pacific Coast is a very good resource for cruising the west coast and has this to say about Depoe Bay
"Unless you are very familiar with this entrance do not enter in rough weather or at night even though flood lights illuminate the passage to the inner basin. There is a dangerous surge in the narrow, curved 15m (50 ft) wide entrance. The vessel must wait for a period of smoother waves when entering to avoid being pushed onto the rocks on the south side. Then in order to pass under the bridge into the harbor apply power to avoid the surge effects"
Wifey B: We don't do inlets at night if not very easy ones we're very familiar with. Not even with night vision. We'll do Port Everglades but not many more.
On the Oregon Coast, the Coast Guard is always there to advise you on conditions.